๐ Built by a medical student
โ GMP Certified
๐ฟ Non-GMO
๐ Free US Shipping over $50
Active Nutrition
Finally absorb your B vitamins.
Formulated with the active forms your body actually uses โ no conversion required.
Why active forms matter.
One capsule. The active form. Daily.
- Active methylfolate 15mg โ clinical-strength, not trace amounts
- Bypasses MTHFR conversion โ works regardless of your genetics
- Supports brain, mood & heart health โ methylation is central to how you feel and function
- 120 capsules โ 60-day supply โ two full months of daily support
Never run out.
Choose the option that works for you. Cancel anytime.
Built by a medical student who actually studied this.
I first encountered methylation in a biochemistry lecture during my second year of medical school. We were covering the folate cycle โ how the body converts dietary folate through a series of reactions to produce SAM-e, the universal methyl donor. My professor mentioned a common genetic variant called MTHFR that could significantly impair this process.
After class, I went looking for a supplement that addressed this. What I found was confusion: products marketed around MTHFR that used folic acid, exaggerated claims, and no real explanation of the biology. The brands that knew their science weren't explaining it. The brands doing the explaining didn't know the science.
Vyla exists to close that gap. We make one product โ formulated with the active form your body actually uses โ and we explain exactly why it's built the way it is.
What people are saying
Frequently asked questions
What is 5-MTHF?
5-MTHF (5-methyltetrahydrofolate) is the biologically active form of folate โ the molecule your cells actually use. Unlike folic acid, which requires enzymatic conversion, 5-MTHF is ready to participate in methylation reactions immediately upon absorption.
Do I need to be tested for MTHFR first?
No. 5-MTHF is beneficial for everyone, regardless of MTHFR status. If you carry an MTHFR variant, 5-MTHF bypasses the conversion bottleneck entirely. If you don't, you still get superior bioavailability compared to folic acid.
How is this different from regular folic acid?
Folic acid is synthetic and must be converted by the MTHFR enzyme before your body can use it. 5-MTHF is the end-product form โ already converted, immediately bioavailable, and effective regardless of your genetics.
When will I notice a difference?
Most people notice changes in energy and mental clarity within 4โ8 weeks of consistent daily use. Methylation support is cumulative โ results build over time. For best results, take one capsule daily with or without food.
Is this safe to take daily?
Yes, at the recommended dose of one capsule daily. 5-MTHF is well-tolerated and has been studied extensively. As with any supplement, consult your healthcare provider if you are pregnant, nursing, or taking medications.